Siyar Bahadir, MD, PhD(c)

Neurosurgeon-scientist building clinical and research tools.

I work across clinical AI, computational anatomy, bioelectronic medicine, neuroimaging and experimental neuroscience. My work usually starts with a concrete problem in a clinical or research workflow and ends as a dataset, analysis pipeline, interactive tool, device concept or publication that other people can use.

450+ neurosurgical operations Elmezzi Scholar · Feinstein Institutes 2 provisional patent applications Glen Cove, NY
Selected work

Tools, datasets and workflows

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Human anatomy · Bioelectronic medicine

Human Vagus Nerve Atlas

A standardized, surgically relevant map of organ-specific branch emergence from the human vagus nerve, with open data, reproducible analysis and an interactive explorer.

Published in Brain Stimulation; presented in an invited NIH SPARC seminar.
Neuroplastic surgery · Scientific communication

Neuroplastic Anatomy

AI-assisted generation of publication-quality anatomy illustrations for scientific and educational use, developed for work with the Society for Neuroplastic Surgery.

Outputs are being incorporated into Society educational supplements.
Open live ↗
Research infrastructure · AI

Noospera

A system for organizing long-running AI conversation histories into searchable maps of projects, themes and research development.

Open live ↗
Neuroimaging · Product development

CerebroMap

Independent work on computational brain mapping, tractography, automated MRI analysis, 3D visualization and cloud-based neuroimaging workflows.

Research

Current and recent programs

The broader work behind the public tools.

01

Human vagus nerve and nodose ganglion mapping

Human cadaveric anatomy, tissue clearing, light-sheet microscopy, single-fiber reconstruction, molecular/spatial profiling and quantitative mapping for selective bioelectronic medicine. Part of NIH-supported human vagus mapping work at the Feinstein Institutes.

Light-sheet microscopySHANEL / cleared tissueFiber trackingSpatial & molecular anatomy3D reconstruction
02

Peripheral-nerve imaging and experimental tooling

Built workflows for intact human nerve and ganglion imaging, including custom holders, mounting systems, access tools and 3D-printed research devices. Some device concepts became the basis for provisional patent work.

3D printingDevice prototypingMicroscopy hardwareImage analysis
03

Neuroplastic and reconstructive surgery

Computational methods for cranial reconstruction, including automated 3D deformity measurement, transcranioplasty ultrasound through sonolucent implants, and anatomy/education tools for the Society for Neuroplastic Surgery.

Quantitative morphologyUltrasoundCranioplastyScientific illustration
04

Clinical AI and evaluation

Clinical evaluation of language models, AI-assisted research workflows, and an invited review for Neurosurgery on data quality, leakage, validation, interpretability, reproducibility and clinical relevance in neurosurgical AI studies.

LLM evaluationEvaluation harnessesAgentic workflowsRAG / embeddings
05

Quantitative neurosurgical imaging

Work spanning normal-pressure hydrocephalus, connectomics, tractography, cranial morphology, AR/head-mounted fiber tractography, 7T ex-vivo imaging and imaging-to-operative-planning workflows.

MRIDTI / fMRIConnectomicsTractography3D planning
Selected publications

Research outputs

2026A standardized, surgically relevant map for emergence of organ-specific branches from the human vagus nerve. Brain Stimulation. 2026Artificial Intelligence and the Jagged Frontier of Clinical Reasoning: Lessons from Neurosurgery. Neurosurgery.
2026Automated 3D Measurement and Topographic Representation for Quantitative Assessment of Deformity Correction in Cranioplasty. Operative Neurosurgery. Accepted.
2026The sixth bioelectronic medicine summit: Neurotechnologies for individuals and communities. Bioelectronic Medicine.
2025Augmented reality in cranial surgery: Surgical planning and maximal safety in resection of brain tumors via head-mounted fiber tractography. Clinical Neurology and Neurosurgery.
2024Chat-GPT on brain tumors: diagnosis and treatment planning for example neuro-oncology cases. Clinical Neurology and Neurosurgery.
2024Ultrahigh-resolution 7-Tesla MRI and DTI of the ex vivo human brainstem-cerebellum complex. Frontiers in Human Neuroscience.
2023Virtual neurosurgery anatomy laboratory: a collaborative and remote education experience in the metaverse. Surgical Neurology International.
2021Group-level ranking-based hubness analysis of the human brain connectome. Frontiers in Neuroscience.
2020Emergency diagnosis and triage with artificial intelligence in intracranial hemorrhage. Journal of Medical Innovation and Technology.
Talks & recognition

Selected invitations

Rockefeller UniversityLight Sheet Microscopy Workshop · 2026
NIH SPARCInvited seminar on the human vagus atlas · 2026
UT Dallas / Center for Pain StudiesInvited presentation on human nodose and peripheral-nerve methods · 2026
Lenox Hill HospitalComputational Methods for Neuroplastic & Reconstructive Surgery · 2026
Brain Economy SummitInvited guest during UNGA80 · 2025
Congress of Neurological SurgeonsOral presentation, quantitative cranioplasty · 2025
Research RenaissancePodcast conversation on neurosurgery, vagus anatomy and bioelectronic medicine · 2026
Elmezzi ScholarFeinstein Institutes for Medical Research · 2023–present
Background

Clinical training and experience

2023–present
Feinstein Institutes for Medical Research / Elmezzi Graduate School

Elmezzi Scholar and PhD candidate in Bioelectronic Medicine. Human vagus and nodose mapping, peripheral-nerve imaging, computational anatomy and translational device work.

2023
Anamur State Hospital

Attending neurosurgeon after residency, managing emergency neurosurgical and trauma care in a public hospital.

2017–2023
Hacettepe University · Neurosurgery Resident / Chief Resident

Comprehensive neurosurgical training with 450+ operations. Built brain-mapping, tractography and quantitative imaging workflows alongside clinical practice.

2015–2017
Turkish Ministry of Health · Rural Emergency Physician / EMS Coordination

Frontline emergency care, triage, resuscitation, long-distance transfers and regional EMS coordination in Muş, Türkiye.

AI & software

Python, LLM application development, model evaluation, evaluation harnesses, tool use, agentic workflows, RAG/embeddings, computer vision, deep learning, SQL, APIs, deployment and interactive visualization.

Clinical computation

MRI, CT, DTI/fMRI, tractography, connectomics, computational anatomy, 3D reconstruction, radiomics, quantitative morphology and operative planning.

Experimental

Light-sheet microscopy, tissue clearing, immunohistochemistry, molecular/spatial anatomy, human cadaveric tissue processing, segmentation and fiber tracking.

Devices & prototyping

3D printing, CAD-style modeling, surgical guides, anatomical access modeling, prototype iteration, cadaveric testing and surgeon-engineer workflow translation.

Contact

Research, clinical technology and collaboration.

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